Content » Vol 48, Issue 4

Original report

Convergent validity and responsiveness of the EQ-5D utility weights for stroke survivors

Wen-Shian Lu, Sheau-Ling Huang, Jeng-Feng Yang, Mei-Hsiang Chen, Ching-Lin Hsieh, Chia-Yeh Chou
School of Occupational Therapy, Chung Shan Medical University Hospital, Taichung City, Taiwan
DOI: 10.2340/16501977-2069


Objective: This prospective study examined the convergent validity and responsiveness of the EuroQoL-5 Dimensions Health Questionnaire (EQ-5D) utility weights in stroke survivors at the subacute stage.
Methods: Repeated assessments were conducted in rehabilitation wards of a medical centre. A study cohort was recruited from inpatients (n = 478). A total of 342 participants (71.5%) completed 2 assessments; 1 at ward admission and 1 before hospital discharge. Outcome measures, including the Barthel Index (BI), Patient Health Questionnaire (PHQ-9) and EQ-5D, were administered at ward admission and before hospital discharge.
Results: The validity of the EQ-5D utility weights was assessed by comparison with the scores of the BI and PHQ-9. The absolute values of Pearson correlation coefficients ranged from 0.40 to 0.52 for the association of EQ-5D utility weights with BI scores and PHQ-9 scores at admission and before hospital discharge. The EQ-5D utility weights had a moderate effect size (0.76), moderate standardized response mean (0.74), and a significant difference (paired t-value = 13.7, p < 0.001) between baseline and follow-up in their ability to detect changes in the health status of stroke survivors staying in a rehabilitation ward.
Conclusion: This study supports the use of the EQ-5D utility weights as a valid and responsive instrument for performing cost-utility analyses of stroke survivors, including those with higher levels of dependence, at the subacute stage.

Lay Abstract


Do you want to comment on this paper? The comments will show up here and if appropriate the comments will also separately be forwarded to the authors. You need to login/create an account to comment on articles. Click here to login/create an account.