Content » Vol 46, Issue 4

Original report

Health-related quality of life in fibromyalgia and refractory angina pectoris: A comparison between two chronic non-malignant pain disorders

Paulin Andréll , Tomas Schultz, Kaisa Mannerkorpi, Lena Nordeman, Mats Börjesson, Clas Mannheimer
Department of Molecular and Clinical Medicine/Multidisciplinary Pain Center, Institute of Medicine, 416 85 Göteborg, Sweden. E-mail:
DOI: 10.2340/16501977-1279


Objective: To compare health-related quality of life in 2 different populations with chronic pain: patients with fibromyalgia and patients with refractory angina pectoris. Previous separate studies have indicated that these patient groups report different impacts of pain on health-related quality of life.
Methods: The Short-Form 36 was used to assess health-
related quality of life. In order to adjust for age and gender differences between the groups, both patient groups were compared with age- and gender-matched normative controls. The difference in health-related quality of life between the 2 patient groups was assessed by transforming the Short-Form 36 subscale scores to a z-score.
Results: The patients with fibromyalgia (n = 203) reported poorer health-related quality of life in all the subscale scores of Short-Form 36 (p < 0. 05–0. 0001) than the patients with refractory angina (n = 146) when both groups were compared with their corresponding normal population (z-score).
Conclusion: Patients with fibromyalgia experience greater impairment in health-related quality of life compared with the normal population than do patients with refractory angina pectoris, despite the fact that the latter have a potentially life-threatening disease. The great impairment in health-
related quality of life in patients with fibromyalgia should be taken into consideration when planning rehabilitation.

Lay Abstract


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