Content » Vol 42, Issue 3

Original report

Ratio of early mitral inflow peak velocity to flow propagation velocity predicts training effects of cardiac rehabilitation in patients after acute myocardial infarction

Cheng-Chih Chung, Wei-Chun Huang, Kuan-Rau Chiou, Ko-Long Lin, Feng-Yu Kuo, Chin-Chang Cheng, Shih-Hung Hsiao, Chun-Peng Liu


DOI: 10.2340/16501977-0514

Abstract

Objective: To use the ratio of early mitral inflow peak velocity (E) to mitral flow propagation velocity (FPV) measured in the early phase of myocardial infarction (early phase E/FPV) to evaluate the training effects of 8 weeks’ cardiopulmonary rehabilitation in patients post-myocardial infarction.
Design: Single-blinded, randomized control trial.
Participants: Eighty-seven patients with acute myocardial infarction who had undergone primary coronary intervention.
Methods: Participants were enrolled randomly to either the cardiac rehabilitation or the control group. The rehabilitation group followed an 8-week supervised rehabilitation programme. All patients completed exercise testing and echo-
cardiography at both the beginning and at 8-week follow-up.
Results: The value of E/FPV was significantly reduced at 8-week follow-up in the rehabilitation group (p = 0.005). After cardiac rehabilitation, the increase in peak VO2 (p = 0.002) and cardiac clinical outcome (composition of mortality, cardiac readmission rate, and revascularization rate) (p = 0.001) were significantly greater in patients with an early phase E/FPV < 1.5 than in patients with early phase E/FPV ≥ 1.5. There were no significant differences in the increase in peak V O2 and cardiac clinical outcome in patients with early phase E/FPV ≥ 1.5.
Conclusion: Early phase E/FPV < 1.5 predicts more beneficial effects of cardiac rehabilitation in post-acute myocardial infarction patients who have undergone primary coronary intervention.

Lay Abstract

Comments

Do you want to comment on this paper? The comments will show up here and if appropriate the comments will also separately be forwarded to the authors. You need to login/create an account to comment on articles. Click here to login/create an account.