Content » Vol 29, Issue 2

Original report

Comorbidity of personality disorders and major depression in patients with somatoform pain disorders or medical illnesses with long-standing work disability

L Ekselius, M Eriksson, L von Knorring, J Linder
Department of Psychiatry, Uppsala University Hospital, Sweden.
DOI: 10.2340/165019771997299196


The comorbidity between major depression and personality disorders in patients with long-standing work disability at a rehabilitation clinic was investigated. Sixty patients with a somatoform pain disorder and 66 patients with different medical illnesses were assessed by means of a self rating scale for major depression, and the SCID screen personality disorder questionnaire. In the total series, 27% of the patients had a diagnosis of major depression and 34. 9% had at least one personality disorder. Personality disorders were significantly more common in patients with medical illness than in patients with a somatoform pain disorder. There was a high frequency of comorbidity between major depression and personality disorders, especially borderline and avoidant personality disorders. If this is due to a common pathogenetic mechanism, it could explain why SSRIs are effective in both depression and some personality disorders.

Lay Abstract


Do you want to comment on this paper? The comments will show up here and if appropriate the comments will also separately be forwarded to the authors. You need to login/create an account to comment on articles. Click here to login/create an account.