Content » Vol 52, Issue 9

Special report

Rehabilitative of COVID-19 patients with acute lower extremity Ischemia and amputation

Luigia Brugliera, Alfio Spina, Paola Castellazzi, Paolo Cimino, Pietro Arcuri, Maria Grazia Deriu, Chiara Zanetta, Sara Monica Angelone, Jody Filippo Capitanio, Federica Alemanno, Carlo Meloni, Giuseppe D'Angelo, Elise Houdayer, Jubin Abutalebi, Pietro Mortini, Sandro Iannaccone
Department of Rehabilitation and Functional Recovery, I.R.C.C.S. San Raffaele Scientific Institute, Vita-Salute University, Milan, Italy.
DOI: 10.2340/16501977-2714


Objective: To evaluate the clinical characteristics and rehabilitation management of patients who undergo amputation for COVID-19-associated coagulopathy.
Methods: Clinical and laboratory data for 3 patients were analysed and their rehabilitative management discussed.
Results: The medical records of 3 patients who had undergone amputation due to acute lower extremity ischaemia and who were provided with rehabilitation in our COVID-19 unit were reviewed.
Conclusion: Coagulation changes related to SARS-CoV-2 may complicate recovery from this devastating disease. The rehabilitation management of amputated patients for COVID-19 acute lower extremity ischaemia is based on a multilevel approach for clinical, functional, nutritional and neuropsychological needs. Based on this limited experience, a dedicated programme for this specific group of patients seems advantageous to warrant the best functional outcome and quality of life.

Lay Abstract

COVID-19 is a devastating disease, which, in addition to pulmonary manifestations, causes several syndromes. Alteration of the coagulation system leads to thrombotic sequelae, which are typically associated with severe manifestations of SARS-CoV-2. These disorders can cause acute ischaemia of the lower limbs, necessitating amputation. This study reports the rehabilitation needs of 3 patients, highlighting the importance of a multidisciplinary tailored approach. Correct evaluation of the needs of this specific group of patients is essential to improve their chances of the optimum functional outcome and quality of life.


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