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Violaceous Papules of the Back: A Quiz

Violaceous Papules of the Back: A Quiz

Rym Benmously-Mlika, Houda Hammami and Incaf Mokhtar

Dermatology Department, Habib Thameur Hospital, N8 Ali Ben Ayed Street, 1008 Tunis, Tunisia. E-mail: rym.benmously@rns.tn

A 13-year-old boy presented to our dermatology department with a 3-month history of recurrent violaceous papules on his back. His previous medical history was otherwise unremarkable.

One papule had been excised by another physician 4 weeks earlier. Clinical examination revealed the presence of multiple small violaceous papules of 0.5 to 1.5 cm in diameter surrounding the excision site (Fig. 1).

3351fig1.tif

Fig. 1. Multiple small violaceous papules of 0.5 to 1.5 cm in diameter surrounding the excision site.

Histological analysis of a biopsy specimen taken from one of the papules revealed lobules of angiomatous tissue within the papillary dermis (Fig. 2a), containing large numbers of vessels whose lumens were covered by normal-looking endothelial cells (Fig. 2b).

3351fig2.tif

Fig. 2. (a) Lobules of angiomatous tissue within the papillary dermis (H&E, ×20). (b) Abundant vessels with lumens covered by normal-looking endothelial cells (H&E, ×40).

What is your diagnosis? See next page for answer.

Violaceous Papules of the Back: A Comment

Acta Derm Venereol 2011; 91: 491–494 (contd).

Diagnosis: Recurrent pyogenic granuloma or Warner and Wilson-Jones syndrome (1, 2)

A diagnosis of Kaposi’s sarcoma disease or melanoma can be excluded based on the observed histopathological features.

Recurrent pyogenic granuloma describes the appearance of multiple satellite papules around the site of a pyogenic granuloma between 1 and 4 weeks after its initial treatment. This phenomenon usually affects young patients. As in our patient, lesions are often located on the back and the scapular area.

The release of vascular endothelial growth factor after trauma is a relevant pathogenic mechanism (3). Recurrent pyogenic granuloma is a benign condition in which spontaneous involution occurs within 6 to 12 months.

Nevertheless, several possible treatments have been described (4, 5). These include surgical excision, curettage, electric cauterisation, carbon dioxide laser therapy, compression, cryotherapy, and the use of an intense pulsed light system. The recurrence rate has been estimated at between 16 and 50% (6, 7).

References

  • Warner J, Jones EW. Pyogenic granuloma recurring with multiple satellites: a report of 11 cases. Br J Dermatol 1968; 80: 218–227.
  • Senser M, Derancourt C, Blanc D, Van Landuyt H, Laurent R. Granulome pyogénique récurrent ou syndrome de Warner et Wilson-Jones. Arch Pédiatr 1997; 4: 653–655.
  • Deroo M, Eeckhout I, Naeyaert JM. Eruptive satellite vascular malformations after removal of a melanocytic naevus. Br J Dermatol 1997; 137: 292–295.
  • Blickenstaff RD, Roenigk RK, Peters MS, Goellner JR. Recurrent pyogenic granuloma with satellitosis. J Am Acad Dermatol 1989; 21: 1241–1214.
  • Paradela S, Del Pozo J, Martinez W, Fernandez-Jorge B, Rodriguez-Lozano J, Yebra-Pimentel T, et al. Pyogenic granuloma: satellitosis after carbon dioxide laser vaporization resolved with an intense pulsed light system. Derm Surg 2007; 33: 104–108.
  • Dillman AM, Millar RC, Hansen RC. Multiple pyogenic granulomata in childhood. Pediatr Dermatol 1991; 8: 28–31.
  • Tursen U, Demirkan F, Ikizoglu G. Giant recurrent pyogenic granuloma on the face with satellitosis responsive to systemic steroids. Clin Exp Dermatol 2004; 29: 40–41.