Content » Vol 89, Issue 6

Erratum

Erratum

In: Mosterd B, Arits AHMM, Thissen MRT, Kelleners-Smeets NWJ. Histology-based Treatment of Basal Cell Carcinoma. Acta Derm Venereol 2009; 89: 454–458 Table II is incorrect. The changes are highlighted in the Table below.

Table II. Randomized controlled trials investigating treatment of clinically and histologically confirmed nodular, aggressively growing or recurrent basal cell carcinoma (BCC)

Ref.

Intervention

BCC,
n

Localization

Clearance rate (%)

FU period (months)

Cosmetic outcome

Conclusion

Nodular basal cell carcinoma

12

Excision

36

Face (scalpel and neck excluded)

98.3a

48

87% gooda

SE higher CR than RTa

SE better CO than RTa

RT

41

92.5a

69% gooda

30

CS

51

Head and neck area

80.4

60

38.5% goodb

SE and CS comparable CR

SE better CO than CS

Excision

45

91.6

79.8% goodb

31

Excision

53

Limbs, trunk, head/neck (high risk areas excluded)

96c

60

54% excellent/good

SE higher CR than MAL-PDT

MAL-PDT

52

86 c

87% excellent/good

32

Excision

All (BCC on concave areas excluded)

97.7

36

Not investigated

SE higher CR than ALA-PDT

ALA-PDT

69.7

Aggressively growing basal cell carcinoma

12

Excision

36

Face (scalpel and neck excluded)

98.3a

48

87% gooda

SE higher CR than RTa

SE better CO than RTa

RT

41

92.5a

69% gooda

28

Excision

199

Face

95.9

60

Not investigated

SE and MMS comparable CR

MMS

198

97.5

Recurrent basal cell carcinoma

28

Excision

100

Face

97.6

60

Not investigated

MMS higher CR than SE

MMS

102

87.9

aResults for total study group, including other histological subtypes with no separate analysis available for nodular, aggressively growing and recurrent basal cell carcinoma, respectively, baverage of cosmetic evaluation of 6 persons including professionals and laymen, cnon-responders after 3 months excluded from this analysis.

PDT: photodynamic therapy; SE: surgical excision; CR: clearance rate; FU: follow-up; CO: cosmetic outcome; CS: cryosurgery; RT: radiotherapy; ALA: aminolevulinic acid; MAL: methyl aminolevulinate; MMS: Mohs’ micrographic surgery.