HLA-DR and DQ antigens in lichen planus
Valsecchi R, Bontempelli M, Rossi A, Bellavita P, Barcella A, Di Landro A, Cainelli T.
DOI: 10.2340/00015555687780
Abstract
A study on HLA-DR and DQ typing in 40 patients with lichen planus (26 males and 14 females) and in 92 normal blood donors of both sexes was performed. Twenty-seven patients had cutaneous lesions, 11 cutaneous and mucosal involvement and 2 patients had oral erosive lesions. Serological typing revealed a highly significant increase of HLA-DR 1 antigen in the patient group. No difference has been observed on the prevalence of DR1 antigen among the different clinical status of the disease.
Significance
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