Content » Vol 67, Issue 6

Human epidermal Langerhans´ cells in bullous pemphigoid

Emtestam L, Hovmark A, Lindberg M, Asbrink E.
DOI: 10.2340/0001555567529532

Abstract

Through the epidermal analysis of 13 patients with bullous pemphigoid compared to controls, using OKT6 monoclonal antibodies on the light microscopic level and electron-microscopy, we found a redistribution of the Langerhans´ cells towards the basal membrane in combination with an increased total number of Langerhans´ cells. This redistribution was also noted in clinically normal skin from patients with bullous pemphigoid. The findings may be consistent with the theory of antigen presentation.

Significance

Supplementary content

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