Reduced levels of histidine and urocanic acid in suction blister fluids from patients with psoriasis
Juhlin L, Shroot B, Martin B, Caron JC.
DOI: 10.2340/0001555566295300
Abstract
Metabolites of histidine were determined by high performance liquid chromatography in suction blister fluids from lesions and normal appearing skin of patients with psoriasis and from healthy subjects. There was a significant decrease in the levels of histidine and urocanic acid in the samples obtained from patients with psoriasis as compared to healthy subjects. Virtually only the E-isomer of urocanic acid was detected.
Significance
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