Content » Vol 62, Issue 5

Sjögren-Larsson syndrome: microscopic and scanning electron microscopic findings in replicas of the skin

Jagell S, Hofer PA.
DOI: 10.2340/0001555562397400

Abstract

Replicas of the skin below the cubital fossa were made in 29 SLS patients with an age range of 8 days to 69 years. The skin surface patterns differed from those in healthy controls. The papillomatosis observed in most SLS replicas seemed to appear during the first year or years of life and to increase in some patients with increasing age, but seemed to diminish again in middle-aged and older SLS patients. Other common features were the occurrence of longitudinal and transverse furrows. All these findings in SLS patients could, at least in part, represent an exaggeration of the normal skin surface pattern. The use of replicas for diagnostic purposes is commented on.

Significance

Supplementary content

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