Effects of short-wave ultraviolet light (UVB) on delayed hypersensitivity in the guinea pig
J. Austad, N.J. Mørk
DOI: 10.2340/0001555562133136
Abstract
Guinea pigs, previously sensitized to dinitrochlorobenzene (DNCB), were exposed to varying doses of UVB radiation on the right flank for a period of 12 days. The response to an elicitation dose of DNCB was diminished in the irradiated skin immediately after UV treatment. This effect was dose-dependent. No reduction in the response could be demonstrated in unexposed skin. One week after UVB treatment the response to DNCB was increased, and after 2 weeks there was a normal eczematous reaction after application of DNCB.
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