Natsuki Kuraishi, Yayoi Nagai, Michiko Hasegawa, Osamu Ishikawa
DOI: 10.2340/00015555-0758

Cutaneous adverse effects of imatinib mesylate (Glivec®) are common and various types of skin eruptions have been reported. We report here a 57-year-old man who presented with lichen planus-like lesions on his extremities and palmoplantar hyperkeratosis due to the use of imatinib mesylate for chronic myeloid leukaemia. The skin lesions improved after discontinuation of imatinib mesylate but re-administration of the drug at a lower dose provoked a mild recurrence. He could, however, continue to take the drug at the lower dose and his skin lesions were well-controlled by topical corticosteroid treat­ment. The literature on lichenoid drug eruption due to imatinib mesylate is reviewed.