Intractable Chronic Pruritus in a 67-year-old Man
                
        Elke Weisshaar
                    DOI: 10.2340/00015555-0520
                    
        
                
   
                Abstract
                
        Chronic pruritus (> 6 weeks) can be caused by skin diseases and systemic diseases, including malignancies. It is a distressing symptom that requires a precise medical history, thorough physical examination, laboratory and radiological diagnostics. The interpretation of results may sometimes be difficult and may often reveal several patho¬logical findings. This case report demonstrates prostate cancer as a possible underlying disease in a patient with chronic pruritus. Therapy with the selective serotonin  reuptake inhibitor paroxetine significantly relieved  pruritus, but was less effective when external therapy was discontinued. Most pruritus patients need conse¬cutive or combined aetiological and symptomatic (topical  and systemic) therapy.                 
                Significance
                
                        
                    
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